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From the AI-on-drugs department: Google DeepMind's chief business officer says Alphabet's drug-discovery company Isomorphic Labs "is preparing to launch human trials of AI-designed drugs," according to a report in Fortune, "pairing cutting-edge AI with pharma veterans to design medicines faster, cheaper, and more accurately."
"There are people sitting in our office in King's Cross, London, working, and collaborating with AI to design drugs for cancer," said Colin Murdoch [DeepMind's chief business officer and president of Isomorphic Labs]. "That's happening right now."
After years in development, Murdoch says human clinical trials for Isomorphic's AI-assisted drugs are finally in sight. "The next big milestone is actually going out to clinical trials, starting to put these things into human beings," he said. "We're staffing up now. We're getting very close."
The company, which was spun out of DeepMind in 2021, was born from one of DeepMind's most celebrated breakthroughs, AlphaFold, an AI system capable of predicting protein structures with a high level of accuracy. Interactions of AlphaFold progressed from being able to accurately predict individual protein structures to modeling how proteins interact with other molecules like DNA and drugs. These leaps made it far more useful for drug discovery, helping researchers design medicines faster and more precisely, turning the tool into a launchpad for a much larger ambition... In 2024, the same year it released AlphaFold 3, Isomorphic signed major research collaborations with pharma companies Novartis and Eli Lilly. A year later, in April 2025, Isomorphic Labs raised $600 million in its first-ever external funding round, led by Thrive Capital. The deals are part of Isomorphic's plan to build a "world-class drug design engine..."
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From the enter-the-dragon department: "The China Film Foundation, a nonprofit fund under the Chinese government, plans to use AI to revitalize 100 kung fu classics including Police Story, Once Upon a Time in China and Fist of Fury, featuring Jackie Chan, Jet Li and Bruce Lee, respectively," reports the Los Angeles Times.
"The foundation said it will partner with businesses including Shanghai Canxing Culture & Media Co., which will license 100 Hong Kong films to AI companies to reintroduce those movies to younger audiences globally."
The foundation said there are opportunities to use AI to tell those stories through animation, for example. There are plans to release an animated version of director John Woo's 1986 film A Better Tomorrow that uses AI to "reinterpret" Woo's "signature visual language," according to an English transcript of the announcement....
The project raised eyebrows among U.S. artists, many of whom are deeply wary of the use of AI in creative pursuits. The Directors Guild of America said AI is a creative tool that should only be used to enhance the creative storytelling process and "it should never be used retroactively to distort or destroy a filmmaker's artistic work... The DGA strongly opposes the use of AI or any other technology to mutilate a film or to alter a director's vision," the DGA said in a statement. "The Guild has a longstanding history of opposing such alterations on issues like colorization or sanitization of films to eliminate so-called 'objectionable content', or other changes that fundamentally alter a film's original style, meaning, and substance."
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From the summer-breaks department: "A growing group of young, college-educated Americans are struggling to find work," reports the Minnesota Star Tribune, "as the unemployment rate for recent graduates outpaces overall unemployment for the first time in decades."
While the national unemployment rate has hovered around 4% for months, the rate for 20-something degree holders is nearly 6%, data from the Federal Reserve Bank of New York shows. [And for young workers (ages 22 to 27) without a degree it's 6.9%.] The amount of time young workers report being unemployed is also on the rise.
Economists attribute some of the shift to normal post-pandemic cooling of labor market, which is making it harder for job-seekers of all ages to land a gig. But there's also widespread economic uncertainty causing employers to pull back on hiring and signs AI could replace entry-level positions....
Business schools nationwide were among the first to see the labor market shift in early 2023 as tech industry cuts bled into other sectors, said Maggie Tomas, Business Career Center executive director at Carlson. Tariffs and stock market volatility have only added to the uncertainty, she said. In 2022, when workers had their pick of jobs, 98% of full-time Carlson MBA graduates had a job offer in a field related to their degree within three months of graduation, according to the school. That number, which Tomas said is usually 90% or higher, dropped to 89% in 2023 and 83% in 2024.
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From the flight-risk department: Investigators of a deadly Boeing 787 crash "are studying possible dual engine failure as a scenario that prevented the Boeing Co. 787 jet from staying airborne," reports Bloomberg:
Pilots from the airline reenacted the doomed aircraft's parameters in a flight simulator, including with the landing gear deployed and the wing flaps retracted, and found those settings alone didn't cause a crash, according to people familiar with the investigation. [Also, analysis of the wreckage "suggests the wing flaps and slats, which help an aircraft increase lift during takeoff, were extended correctly."]
The result, alongside the previous discovery that an emergency-power turbine deployed seconds before impact, has reinforced the focus on a technical failure as one possible cause, said the people, who asked not to be identified discussing nonpublic deliberations... [The turbine deploys "in the case of electrical failure," the article points out, and "was activated before the plane crashed, according to previous findings. That fan helps provide the aircraft with vital power, though it's far too small to generate any lift."]
Pilots who reviewed the footage have pointed to the fact that the landing gear was already partially tilted forward, suggesting the cockpit crew had initiated the retraction sequence of the wheels. At the same time, the landing-gear doors had not opened, which pilots say might mean that the aircraft experienced a loss of power or a hydraulic failure — again pointing to possible issues with the engines that provide the aircraft's electricity.
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From the happy-Independence-Day department: "California residents who lit illegal fireworks over the July 4 holiday may be in for a nasty surprise in the mail thanks to covert fire department operations," reports SFGate.
"A number of California cities, including Sacramento, have begun using drones to locate people shooting off illegal fireworks."
From Wednesday to Saturday night, the Sacramento Fire Department's special fireworks task force patrolled the streets with unmarked cars and drones, focusing on neighborhoods where they've had prior complaints. Task force officers and the drones took photos of the illegal activity, and within 30 days the property owner where the fireworks were used could receive a fine in the mail...
This year, Sacramento upped the fine to $1,000 for the first firework, $2,500 for the second and $5,000 per firework after that. If you lit a firework on city property, such as a park or a school, the fine goes up to $10,000 each. There's no limit to how many fines you can be issued... This year, a number of cities across the state announced they would be using drones to find scofflaws, among them Indio, Riverside, Hemet, Brea and towns in Tulare County...
Fox40 reported on Saturday that around 60 citations were being prepared in Sacramento, with more likely on the way as fire officials review surveillance footage.
Last year for illegal fireworks, one Sacramento-area resident received a $100,000 fine.
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From the long-march department: China "is pouring money into building an AI supply chain with as little reliance on the U.S. as possible," reports the Wall Street Journal.
And now Chinese AI companies "are loosening the U.S.'s global stranglehold on AI," reports the Wall Street Journal, "challenging American superiority and setting the stage for a global arms race in the technology."
In Europe, the Middle East, Africa and Asia, users ranging from multinational banks to public universities are turning to large language models from Chinese companies such as startup DeepSeek and e-commerce giant Alibaba as alternatives to American offerings such as ChatGPT... Saudi Aramco, the world's largest oil company, recently installed DeepSeek in its main data center. Even major American cloud service providers such as Amazon Web Services, Microsoft and Google offer DeepSeek to customers, despite the White House banning use of the company's app on some government devices over data-security concerns.
OpenAI's ChatGPT remains the world's predominant AI consumer chatbot, with 910 million global downloads compared with DeepSeek's 125 million, figures from researcher Sensor Tower show. American AI is widely seen as the industry's gold standard, thanks to advantages in computing semiconductors, cutting-edge research and access to financial capital. But as in many other industries, Chinese companies have started to snatch customers by offering performance that is nearly as good at vastly lower prices. A study of global competitiveness in critical technologies released in early June by researchers at Harvard University found China has advantages in two key building blocks of AI, data and human capital, that are helping it keep pace...
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From the FSF-DDoS department: The Free Software Foundation's services face "ongoing (and increasing) distributed denial of service (DDoS) attacks," senior systems administrator Ian Kelling wrote Wednesday. But "Even though we are under active attack, gnu.org, ftp.gnu.org, and savannah.gnu.org are up with normal response times at the moment, and have been for the majority of this week, largely thanks to hard work from the Savannah hackers Bob, Corwin, and Luke who've helped us, your sysadmins."
"We've shielded these sites for almost a full year of intense attacks now, and we'll keep on fighting these attacks for as long as they continue."
Our infrastructure has been under attack since August 2024. Large Language Model (LLM) web crawlers have been a significant source of the attacks, and as for the rest, we don't expect to ever know what kind of entity is targeting our sites or why.
- In the fall Bulletin, we wrote about the August attack on gnu.org. That attack continues, but we have mitigated it. Judging from the pattern and scope, the goal was likely to take the site down and it was not an LLM crawler. We do not know who or what is behind the attack, but since then, we have had more attacks with even higher severity.
- To begin with, GNU Savannah, the FSF's collaborative software development system, was hit by a massive botnet controlling about five million IPs starting in January. As of this writing, the attack is still ongoing, but the botnet's current iteration is mitigated. The goal is likely to build an LLM training dataset. We do not know who or what is behind this.
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From the celestial-navigations department: Three space probes are leaving our solar system — yet are still functioning. After the two Voyager space probes, New Horizons "was launched in 2006, initially to study Pluto," remembers New Scientist. But "it has since travelled way beyond this point, ploughing on through the Kuiper belt, a vast, wide band of rocks and dust billions of miles from the sun. It is now speeding at tens of thousands of kilometres per hour..."
And it's just performed the first ever example of interstellar navigation...
As it hurtles out of our solar system, NASA's New Horizons spacecraft is so far from Earth that the stars in the Milky Way appear in markedly different positions compared with our own view... due to the parallax effect. This was demonstrated in 2020 when the probe beamed back pictures of two nearby stars, Proxima Centauri and Wolf 359, to Earth.
Now, Tod Lauer at the US National Optical-Infrared Astronomy Research Laboratory in Arizona and his colleagues have used this effect to work out the position of New Horizons... Almost all spacecraft calculate their bearings to within tens of metres using NASA's Deep Space Network, a collection of radio transmitters on Earth that send regular signals out to space. In comparison, the parallax method was far less accurate, locating New Horizons within a sphere with a radius of 60 million kilometres, about half the distance between Earth and the sun. "We're not going to put the Deep Space Network out of business — this is only a demo proof of concept," says Lauer. However, with a better camera and equipment they could improve the accuracy by up to 100 times, he says.
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From the wrong-arm-of-the-law department: A Maine police department has now acknowledged "it inadvertently shared an AI-altered photo of drug evidence on social media," reports Boston.com:
The image from the Westbrook Police Department showed a collection of drug paraphernalia purportedly seized during a recent drug bust on Brackett Street, including a scale and white powder in plastic bags. According to Westbrook police, an officer involved in the arrests snapped the evidence photo and used a photo editing app to insert the department's patch. "The patch was added, and the photograph with the patch was sent to one of our Facebook administrators, who posted it," the department explained in a post. "Unbeknownst to anyone, when the app added the patch, it altered the packaging and some of the other attributes on the photograph. None of us caught it or realized it."
It wasn't long before the edited image's gibberish text and hazy edges drew criticism from social media users. According to the Portland Press Herald, Westbrook police initially denied AI had been used to generate the photo before eventually confirming its use of the AI chatbot ChatGPT. The department issued a public apology Tuesday, sharing a side-by-side comparison of the original and edited images.
"It was never our intent to alter the image of the evidence," the department's post read. "We never realized that using a photoshop app to add our logo would alter a photograph so substantially."
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From the don't-play-with-your-food department: "Scientists have created the first lasers made entirely from edible materials," reports Science magazine "which could someday help monitor and track the properties of foods and medications with sensors that can be harmlessly swallowed."
[The researchers' report] shows that tiny droplets of everyday cooking oils can act like echo chambers of light, otherwise known as lasers. By providing the right amount of energy to an atom, the atom's electrons will excite to a higher energy level and then relax, releasing a photon of light in the process. Trap a cloud of atoms in a house of mirrors and blast them with the right amount of energy, and the light emitted by one excited atom will stimulate one of its neighbors, amplifying the atoms' collective glow...
[The researchers] shot purple light at droplets of olive oil, whose surfaces can keep photons of light bouncing around, trapping them in the process. This reflected light excited the electrons in the oil's chlorophyll molecules, causing them to emit photons that triggered the glow of other chlorophyll molecules — transforming the droplet into a laser. The energy of the chlorophyll's radiation depends on the oil droplets' size, density, and other properties. The study's authors suggest this sensitivity can be exploited to track different properties of food or pharmaceutical products.
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From the land-of-diffusion department: "Apple quietly dropped a new AI model on Hugging Face with an interesting twist," writes 9to5Mac. "Instead of writing code like traditional LLMs generate text (left to right, top to bottom), it can also write out of order, and improve multiple chunks at once."
"The result is faster code generation, at a performance that rivals top open-source coding models."
Traditionally, most LLMs have been autoregressive. This means that when you ask them something, they process your entire question, predict the first token of the answer, reprocess the entire question with the first token, predict the second token, and so on. This makes them generate text like most of us read: left to right, top to bottom... An alternative to autoregressive models is diffusion models, which have been more often used by image models like Stable Diffusion. In a nutshell, the model starts with a fuzzy, noisy image, and it iteratively removes the noise while keeping the user request in mind, steering it towards something that looks more and more like what the user requested...
Lately, some large language models have looked to the diffusion architecture to generate text, and the results have been pretty promising... This behavior is especially useful for programming, where global structure matters more than linear token prediction... [Apple] released an open-source model called DiffuCode-7B-cpGRPO, that builds on top of a paper called DiffuCoder: Understanding and Improving Masked Diffusion Models for Code Generation, released just last month... [W]ith an extra training step called coupled-GRPO, it learned to generate higher-quality code with fewer passes. The result? Code that's faster to generate, globally coherent, and competitive with some of the best open-source programming models out there.
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From the leader-bored department: An anonymous reader shared this report from the San Francisco Standard:
About an hour into my meeting with the undisputed hackathon king of San Francisco, Rene Turcios asked if I wanted to smoke a joint with him. I politely declined, but his offer hardly surprised me. Turcios has built a reputation as a cannabis-loving former professional Yu-Gi-Oh! player who resells Labubus out of his Tenderloin apartment when he's not busy attending nearly every hackathon happening in the city. Since 2023, Turcios, 29, has attended more than 200 events, where he's won cash, software credits, and clout. "I'm always hustling," he said.
The craziest part: he doesn't even know how to code.
"Rene is the original vibe coder," said RJ Moscardon, a friend and fellow hacker who watched Turcios win second place at his first-ever hackathon at the AGI House mansion in Hillsborough. "All the engineers with prestigious degrees scoffed at him at first. But now they're all doing exactly the same thing...." Turcios was vibe coding long before the technique had a name — and was looked down upon by longtime hackers for using AI. But as Tiger Woods once said, "Winning takes care of everything...."
Instead of vigorously coding until the deadline, he finished his projects hours early by getting AI to do the technical work for him. "I didn't write a single line of code," Turcios said of his first hackathon where he prompted ChatGPT using plain English to generate a program that can convert any song into a lo-fi version. When the organizers announced Turcios had won second place, he screamed in celebration.... "I realized that I could compete with people who have degrees and fancy jobs...."
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From the powering-ahead department: "Tesla has launched its new Oasis Supercharger," reports Electrek, "the long-promised EV charging station of the future, with a solar farm and off-grid batteries."
Early in the deployment of the Supercharger network, Tesla promised to add solar arrays and batteries to the Supercharger stations, and CEO Elon Musk even said that most stations would be able to operate off-grid... Last year, Tesla announced a new project called 'Oasis', which consists of a new model Supercharger station with a solar farm and battery storage enabling off-grid operations in Lost Hills, California.
Tesla has now unveiled the project and turned on most of the Supercharger stalls. The project consists of 168 chargers, with half of them currently operational, making it one of the largest Supercharger stations in the world. However, that's not even the most notable aspect of it. The station is equipped with 11 MW of ground-mounted solar panels and canopies, spanning 30 acres of land, and 10 Tesla Megapacks with a total energy storage capacity of 39 MWh. It can be operated off-grid, which is the case right now, according to Tesla.
With off-grid operations, Tesla was about to bring 84 stalls online just in time for the Fourth of July travel weekend. The rest of the stalls and a lounge are going to open later this year.
The article makes that point that "This is what charging stations should be like: fully powered by renewable energy."
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From the problem-sets department: "A computer science degree used to be a golden ticket to the promised land of jobs," a college senior tells the New York Times. But "That's no longer the case."
The article notes that in the last three years there's been a 65% drop from companies seeking workers with two years of experience or less (according to an analysis by technology research/education organization CompTIA), with tech companies "relying more on AI for some aspects of coding, eliminating some entry-level work."
So what do college professors teach when AI "is coming fastest and most forcefully to computer science"?
Computer science programs at universities across the country are now scrambling to understand the implications of the technological transformation, grappling with what to keep teaching in the AI era. Ideas range from less emphasis on mastering programming languages to focusing on hybrid courses designed to inject computing into every profession, as educators ponder what the tech jobs of the future will look like in an AI economy... Some educators now believe the discipline could broaden to become more like a liberal arts degree, with a greater emphasis on critical thinking and communication skills.
The National Science Foundation is funding a program, Level Up AI, to bring together university and community college educators and researchers to move toward a shared vision of the essentials of AI education. The 18-month project, run by the Computing Research Association, a research and education nonprofit, in partnership with New Mexico State University, is organising conferences and roundtables and producing white papers to share resources and best practices. The NSF-backed initiative was created because of "a sense of urgency that we need a lot more computing students — and more people — who know about AI in the workforce," said Mary Lou Maher, a computer scientist and a director of the Computing Research Association.
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From the breeding-success department: Interesting Engineering reports:
Astral Systems, a UK-based private commercial fusion company, has claimed to have become the first firm to successfully breed tritium, a vital fusion fuel, using its own operational fusion reactor. This achievement, made with the University of Bristol, addresses a significant hurdle in the development of fusion energy....
Scientists from Astral Systems and the University of Bristol produced and detected tritium in real-time from an experimental lithium breeder blanket within Astral's multi-state fusion reactors. "There's a global race to find new ways to develop more tritium than what exists in today's world — a huge barrier is bringing fusion energy to reality," said Talmon Firestone, CEO and co-founder of Astral Systems. "This collaboration with the University of Bristol marks a leap forward in the search for viable, greater-than-replacement tritium breeding technologies. Using our multi-state fusion technology, we are the first private fusion company to use our reactors as a neutron source to produce fusion fuel."
Astral Systems' approach uses its Multi-State Fusion (MSF) technology. The company states this will commercialize fusion power with better performance, efficiency, and lower costs than traditional reactors. Their reactor design, the result of 25 years of engineering and over 15 years of runtime, incorporates recent understandings of stellar physics. A core innovation is lattice confinement fusion (LCF), a concept first discovered by NASA in 2020. This allows Astral's reactor to achieve solid-state fuel densities 400 million times higher than those in plasma. The company's reactors are designed to induce two distinct fusion reactions simultaneously from a single power input, with fusion occurring in both plasma and a solid-state lattice.
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From the opening-AI department: "Microsoft has released the source code for the GitHub Copilot Chat extension for VS Code under the MIT license," reports BleepingComputer.
This provides the community access to the full implementation of the chat-based coding assistant, including the implementation of "agent mode," what contextual data is sent to large language models (LLMs), and the design of system prompts. The GitHub repository hosting the code also details telemetry collection mechanisms, addressing long-standing questions about data transparency in AI-assisted coding tools...
As the VS Code team explained previously, shifts in AI tooling landscape like the rapid growth of the open-source AI ecosystem and a more level playing field for all have reduced the need for secrecy around prompt engineering and UI design. At the same time, increased targeting of development tools by malicious actors has increased the need for crowdsourcing contributions to rapidly pinpoint problems and develop effective fixes. Essentially, openness is now considered superior from a security perspective.
"If you've been hesitant to adopt AI tools because you don't trust the black box behind them, this move opensources-github-copilot-chat-vscode/offers something rare these days: transparency," writes Slashdot reader BrianFagioli"
Now that the extension is open source, developers can audit how agent mode actually works. You can also dig into how it manages your data, customize its behavior, or build entirely new tools on top of it. This could be especially useful in enterprise environments where compliance and control are non negotiable.
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Drones Used by California Cities to Patrol for Illegal Fireworks and Issue Fines 2025-07-06 15:40:01
